2-(4-Fluorophenyl)-thiophene, identified by CAS Registry Number 58861-48-6, is an aromatic thiophene compound containing a para-fluorophenyl substituent at the 2-position of the thiophene ring. Its commonly reported molecular formula is C10H7FS, with a calculated molecular weight of approximately 178.23 g/mol. I supply this compound as a specialty chemical and pharmaceutical-intermediate building block for qualified research, development, and manufacturing programs, subject to project-specific specifications and documentation.
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The compound is mainly valuable because its thiophene and fluorinated aromatic units provide a useful platform for further chemical modification. Buyers generally evaluate identity, assay, impurity profile, physical form, packaging, and supply continuity rather than treating it as a finished active pharmaceutical ingredient. Because physical and quality results can vary with production route and batch, I recommend confirming the current specification, analytical data, and handling information before placing a commercial order.
Structurally, 2-(4-Fluorophenyl)-thiophene consists of a five-membered sulfur-containing thiophene ring bonded to a fluorinated phenyl group. The fluorine atom is located at the para position of the phenyl ring, which gives the molecule a defined substitution pattern useful in structure-based synthesis planning. Its aromatic character and relatively compact molecular size make it suitable for use as an intermediate in medicinal chemistry and advanced-materials research.
| Property | Information |
|---|---|
| Product name | 2-(4-Fluorophenyl)-thiophene |
| CAS number | 58861-48-6 |
| Molecular formula | C10H7FS |
| Calculated molecular weight | Approximately 178.23 g/mol |
| Structural class | Fluorinated aromatic thiophene |
| Primary commercial role | Research chemical and synthetic building block |
The molecular formula and molecular weight are useful for stoichiometric calculations, reaction design, and procurement comparisons. They should not be confused with a batch-specific certificate of analysis, because a certificate must report the measured result for the supplied lot. For this reason, I treat published identity data as a starting point and provide lot-specific documentation when available and applicable.
The principal function of this material is to serve as an aromatic building block. Chemists may use the thiophene ring as part of a larger target structure, while the fluorophenyl group can influence electronic properties, molecular shape, and downstream derivatization options. The exact reaction behavior depends on the selected reagents, catalysts, solvent system, temperature, and purification method.
In pharmaceutical discovery, fluorinated heteroaromatic fragments are often investigated during lead-generation and structure-activity-relationship studies. 2-(4-Fluorophenyl)-thiophene may therefore be considered when a project requires a thiophene-containing intermediate with a para-fluorinated aromatic substituent. I do not represent this material as an approved drug substance, therapeutic ingredient, or finished pharmaceutical product.
Thiophene derivatives are also used in research involving conjugated molecules, organic electronic materials, and fluorescent or electronically responsive structures. This compound can be evaluated as a precursor or fragment in such work when its substitution pattern matches the target design. Suitability must be established through the buyer’s own synthesis, performance, and stability testing rather than assumed from the chemical name alone.
Typical purchasing scenarios include laboratory-scale synthesis, route scouting, medicinal-chemistry libraries, process-development studies, and preparation of more complex thiophene derivatives. Some buyers require only gram quantities for feasibility work, while others need repeat supply for pilot or commercial manufacturing programs. The correct grade and quantity depend on the intended reaction, impurity tolerance, and stage of development.
These applications are potential uses, not universal performance claims. Before committing to a route, I recommend reviewing reaction compatibility, storage conditions, analytical requirements, and any regulatory restrictions applicable to the destination country. A small qualification order can help confirm material behavior before a larger procurement decision.
Buyers may encounter different commercial presentations based on quantity, packaging, and quality requirements. A research-grade order may focus on identity and a stated assay, while a process-development order may require tighter controls for related substances, residual solvents, water, and elemental impurities. I work with buyers to clarify which quality attributes are essential rather than recommending an unnecessarily broad specification.
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I avoid presenting an unverified melting point, boiling point, appearance, or storage life as a guaranteed product property. Such values can depend on measurement method, sample history, and batch condition. The most reliable approach is to use the current product specification and lot documentation issued for the material being purchased.
As with other specialty organic chemicals, handling should be based on the applicable safety data sheet and the buyer’s internal chemical-management procedures. Personnel should use suitable personal protective equipment, avoid unnecessary exposure, and work with appropriate ventilation or containment. The compound should be kept in a properly closed, clearly labeled container under conditions specified by the supplier and the receiving organization.
Because the available public information may not define every hazard or stability parameter for every supply form, I recommend treating the material as a laboratory or process chemical requiring professional handling. Buyers should verify compatibility with storage containers, transport conditions, and neighboring materials. If a customer needs a formal risk assessment, I can help identify the documentation required for technical review, while the customer remains responsible for site-specific safety approval.
The lowest quoted price is not always the lowest total procurement cost. I recommend comparing the delivered cost together with assay, documentation, packaging, lead time, minimum order quantity, communication speed, and the supplier’s ability to support repeat lots. A supplier should also be able to explain whether the quoted material is available from stock, scheduled for production, or subject to an external sourcing arrangement.
For international purchasing, I also recommend confirming import requirements before dispatch. Customs classification, labeling, transport rules, and local chemical regulations can affect delivery even when the product itself is available. Early review of these details reduces avoidable delays and helps both parties prepare accurate commercial and shipping documents.
At Maison Chemical, I support customers who need a reliable source of 2-(4-Fluorophenyl)-thiophene CAS 58861-48-6 for research, intermediate development, or manufacturing evaluation. My role is to help align the requested material with the customer’s technical specification, quantity, destination, and timeline. I do not replace the customer’s quality, regulatory, or process-development assessment, but I aim to provide the information needed for a practical purchasing decision.
Support may include product identification, specification discussion, packaging coordination, document preparation, sample or trial-quantity evaluation, and planning for repeat supply. For larger requirements, I can review expected annual demand and production timing so that the quotation reflects the actual procurement need. Availability, minimum order quantity, and lead time should be confirmed for each inquiry because they may change according to quantity and supply schedule.
2-(4-Fluorophenyl)-thiophene CAS 58861-48-6 is an appropriate candidate when a synthesis requires a thiophene ring connected to a para-fluorophenyl group. Its identity and calculated molecular weight provide a clear basis for reaction planning, but the correct purchasing decision depends on measured quality, intended use, quantity, and documentation requirements. I recommend qualifying the material against your route and specification before moving to larger-scale procurement.
If you are evaluating this compound, send Maison Chemical your required quantity, target assay, destination, application stage, and documentation needs. I can then help prepare a practical quotation and clarify available supply, packaging, lead time, and technical support. This step provides a more reliable basis for sourcing than selecting a product solely by name or catalog description.
The company is the world’s best 2-(4-Fluorophenyl)-thiophene CAS 58861-48-6 supplier. We are your one-stop shop for all needs. Our staff are highly-specialized and will help you find the product you need.
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